SEDERE has generated a large number of application notes that describe the very extensive use of the SEDEX Low-Temperature Evaporative Light-Scattering Detection in LC and SFC. Although this is not an exhaustive list, it provides several examples showing how the detector is used to solve a broad range of analytical problems.

For more complete and recent information on ELSD technology and applications, you can also refer to our SEDERE ELSD Bibliography.


Application List table (Sorted alphabetically)

Note: the application note numbered 1 to 141 are old historical application notes. Application notes numbered “ANXXX” are new applications. Clicking on the application note will either provide access to the PDF of the application note or a dedicated webpage.

Technique: CCC=Counter Current Chromatography, GPC=Gel Permeation Chromatography, HPLC=High Performance Liquid Chromatography, SFC=Supercritical Fluid Chromatography.

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CompoundChemical ClassTechniqueApplication Number
Acesulfam – KSweetenerHPLCAN1144
Acetylenecarboxilic AcidOrganic AcidHPLC91
Aconitic AcidOrganic AcidHPLC102
AlanineAmino AcidHPLC114 – 123
Aliphatic AlcoholsFatty AlcoholSFC34
Alkyl
Glucosinolates
ThioglucosideHPLC73
AlkylglycosidesDetergentHPLC25
AlkylglycosidesDetergentSFC27
AndrosteroneSteroidHPLC28
ArabinoseCarbohydrateHPLCAN1
Arachidonic AcidFatty AcidHPLC31
ArginineAmino AcidHPLCAN190
AsparagineAmino AcidHPLC113
AspartameSweetenerHPLCAN1144
Aspartic AcidAmino AcidHPLC114
BisulfanSulfonic EsterHPLC82
BromideAnionHPLC145
CaffeineAlkaloidHPLCAN1
CaffeineAlkaloidSFC12
CalciumCationHPLC106
Beta CaroteneTerpenoidHPLC100
CerebrosidePhospholipidHPLC5
CetylbetaineDetergentHPLC145
Cetylpyridinium
Chloride
AromaticHPLC14
CetrimideAntisepticHPLC103
ChloramphenicolAntibioticSFC12
ChlorideAnionHPLCAN1106
CholesterolSteroidHPLC41
Citric AcidOrganic AcidHPLC38
CitrullineAmino AcidHPLC125
CorticosteroneSteroidHPLC92
CoumarinAroma CompoundHPLCAN1
CyclamateSweetenerHPLCAN1144
CyclodextrinsOligosaccharideHPLC79
CysteineAmino AcidHPLCAN1114 – 115
Decanoic AcidFatty AcidHPLC32
Decyl Beta – D
Glucopyranoside
DetergentHPLC25
Decyl Beta – D
Maltoside
DetergentHPLC25
Decyl SulfateDetergentHPLC145
Dehydro – epi –
Andosterone
SteroidHPLC28
DeoxyriboseCarbohydrateHPLC74
DeoxyriboseCarbohydrateSFC49
DextransCarbohydrateHPLC11
Dextrose (D –
Glucose)
CarbohydrateHPLC144
Dimyristolphosphatidyl
Choline
PhospholipidHPLC95
DioleinLipidHPLC99
Dimyristolphosphatidyl
Glycol
PhospholipidHPLC95
Dipalmitin-1,2LipidHPLCAN1
Dipalmitin-1,3LipidHPLCAN1
Docosanoic AcidFatty AcidSFC3
DocosanolFatty AlcoholSFC34
DodecylcyclophosphoethanolaminePhospholipidHPLC83
DodecylcyclophophocholinePhospholipidHPLC83
DodecylsulfateDetergentHPLC145
DehydrophenylalanineAmino AcidHPLC126
EicosanolFatty AlcoholSFC34
ErgocalciferolVitaminHPLC101
ErythritolPolyolHPLCAN1(2 methods)
EstradiolSteroidHPLC29
EstroneSteroidHPLC29
EthiocolanoneSteroidHPLC28
Ethylene GlycolGlycolHPLC141
EthylvanillinAroma CompoundHPLCAN1
Fatty AcidsFatty AcidCCC48
FluorodopaAmino AcidHPLC133
FructoseCarbohydrateHPLCAN11 – 8 – 11 – 44 – 74 – 75 – 77 – 143
FructoseCarbohydrateSFC10 – 49 – 50
Fructose (Beet)CarbohydrateHPLC45
Fructose (Chervil
Root)
CarbohydrateHPLC47
Fructose
(Tabacco)
CarbohydrateHPLC46
Fumaric AcidOrganic AcidHPLC38
GalactoseCarbohydrateHPLC59
76
Ginseng SaponinsTerpenoidHPLC60
GlucoseCarbohydrateHPLCAN11
GlucoseCarbohydrateSFC10 – 49 – 50
Glucose
(Beet)
CarbohydrateHPLC45
Glucose
(Chervil Root)
CarbohydrateHPLC47
Glucose
(Tabacco)
CarbohydrateHPLC46
Glutamic AcidAmino AcidHPLCAN1115
GlutamineAmino AcidHPLC114
GlycerolHPLCAN1(2 methods)
HexacamegHPLC84
HexacosanolFatty AlcoholSFC34
HexadecanolFatty AlcoholSFC34
Hexyl Beta – D
Glucopyranoside
DetergentHPLC25
HistidineAmino AcidHPLCAN1113
Hormonal SteroidsSteroidHPLC28
InositolPolyolHPLCAN1
Inositol PhophatePolyolHPLC80
IsoleucineAmino AcidHPLCAN1113
LactoseCarbohydrateHPLC11
LactuloseCarbohydrateHPLC105
Lauric AcidFatty AcidHPLC40
Lauric AcidFatty AcidSFC3
Lauryldimethylbenzyl
Ammonium Chloride
DetergentHPLC145
Laurylpyridium
Chloride
DetergentHPLC145
LeucineAmino AcidHPLCAN190
Linoleic AcidFatty AcidHPLC81
97
Lipid PlaceboLipidHPLC95
LubrolDetergentHPLC61
LysineAmino AcidHPLCAN190
Lysophosphatidyl CholinePhospholipidHPLC5
Lysophosphatidyl EthanolaminePhospholipidHPLC98
MagnesiumCationHPLCAN1106
Malic AcidOrganic AcidHPLC38
MaltodextrinsPolysaccarideHPLC35
MaltoseCarbohydrateHPLCAN1
MannitolPolyolHPLC44
MannitolPolyolSFC50
MannoseCarbohydrateHPLC44
MannoseCarbohydrateSFC49
MelibioseCarbohydrateHPLC77
Meso – ErythritolPolyolSFC49
Methyl a,b -D
Glucopyranoside
DetergentHPLC25
MethionineAmino AcidHPLCAN1113
M-InositolPolyolHPLC76
MonooleinLipidHPLC99
MonopalmitinLipidHPLCAN1
MorphineAlkaloidSFC33
Myristic AcidFatty AcidSFC3
NarcotineAlkaloidSFC33
Neohesperidin DihydrochalconeSweetenerHPLCAN1
NeotameSweetenerHPLCAN1
NitrateAnionHPLC106
NorleucineAmino AcidHPLC131
NorvalineAmino AcidHPLC132
OctadecanolFatty AlcoholSFC34
Octyl Beta – D
Galactopyranoside
DetergentHPLC25
Octyl Beta – D
Galactopyranoside
DetergentSFC27
Octyl Beta – D
Glucopyranoside
DetergentHPLC25
Octyl Beta – D
Glucopyranoside
DetergentSFC27
Octyl Beta – D
Xylopyranoside
DetergentHPLC25
Octyl Beta – D
Xylopyranoside
DetergentSFC27
Octyl Beta – GlucosideDetergentHPLC61
Oleic AcidFatty AcidHPLC97
Opium AlkaloidsAlkaloidSFC33
Oxytocyn AcetatePeptideHPLC117
Palmitic AcidFatty AcidHPLCAN197
Palmitic AcidFatty AcidSFC3
ParafilmHydrocarbonHPLC42
ParafilmHydrocarbonSFC43
Para-hydroxy-BenzaldheydeAmroma CompoundHPLCAN1
PeptidesPeptideHPLC93
PhenobarbitalAnticonvulsantSFC12
PhenylalanineAmino AcidHPLCAN1113
PhenylbutazoneNSAIDSFC12
Phosphatidic AcidPhospholipidHPLC5
Phosphatidyl
Choline
PhospholipidHPLC5
Phosphatidyl EthanolaminePhospholipidHPLC5
Phosphatidyl GlycerolPhospholipidHPLC98
Phosphatidyl
Inositol
PhospholipidHPLC5
Phosphatityl SerinePhospholipidHPLC5
PinitolPolyolHPLC56
Polybutylene GlycolPolymerHPLC86
Polyethoxylated
Alcohols
PolymerHPLC87
Polyethoxylated
Alcohols
PolymerSFC87
Polyethylene
Bimodal (High MV)
PolymerGPC70
Polyethylene
Glycol PEG 10 Tridecyl Ether
DetergentHPLC61
Polyethylene
Glycol PEG 1450
Polymertd>HPLC54
Polyethylene
Glycol PEG 1450
PolymerSFC88
Polyethylene
Glycol PEG 300
PolymerHPLC21
Polyethylene
Glycol PEG 300, 400
PolymerSFC51
Polyethylene
Glycol PEG 400
PolymerHPLC23
Polyethylene
Glycol PEG 600
PolymerHPLC24
Polyethylene (NBS
1475)
PolymerGPC69
Polyoxyethylene
Alcohol C12 E7
PolymerHPLC19
Polyoxyethylene
Alcohol C12 E9
PolymerHPLC17
Polyoxyethylene
Alcohol C16 E7
PolymerHPLC20
Polyoxyethylene
Alcohol C16 E10
PolymerHPLC18
Polyoxyethylene
Alcohol C18 E10
PolymerHPLC16
Polyoxyethylene
Alcohols
PolymerHPLC89
Polysaccharides
(In Beer)
CarbohydrateHPLC9
Polysorbate 20PolymerHPLC15
Polystyrene (Dow
1683)
PolymerGPC68
Polystyrene
Standards
PolymerGPC62 – 63 – 64 – 65 – 66 – 67
PotassiumCationHPLCAN1106 – 107 – 111
PrednisoloneSteroidSFC12
ProgesteroneSteroidHPLC28
ProlineAmino AcidHPLC113 – 114 – 134
RaffinoseCarbohydrateHPLC1 – 11 – 74 – 75 – 77
RaffinoseCarbohydrateSFC10
Raffinose (Beet)CarbohydrateHPLC45
Rebaudioside A (from Stevia)SweetenerHPLCAN1(2methods)
RhamnoseCarbohydrateHPLCAN174
SaccharinSweetenerHPLCAN1144
SerineAmino AcidHPLC114
Sodium Dodecyl
Sulfate
DetergentHPLC61
SodiumCationHPLCAN1106
SorbitolPolyolHPLCAN1(2 methods) – 1
SorbitolPolyolSFC50
Soybean Oil
(Hydrolyzed)
LipidHPLC118
SphingomyelinPhospholipidHPLC5
StachyoseCarbohydrateHPLC75
Stearic AcidTriglyceridesHPLC97
Stearic AcidTriglyceridesSFC3
StigmasterolSteroidHPLC97
Succinic AcidOrganic Acidtd>HPLC38
SucraloseSweetenerHPLCAN1143
Sucrose
(Saccharose)
CarbohydrateHPLCAN11 – 8 – 11  – 74 – 75 – 77 – 143
Sucrose
(Saccharose)
CarbohydrateSFC10
Sucrose
(Beet)
CarbohydrateHPLC45
Sucrose
(Chevil Root)
CarbohydrateHPLC47
Sucrose
(Tabacco)
CarbohydrateHPLC46
Sugars
(Mono-Oligosaccharides)
CarbohydrateHPLC76
Sugars
(Douglas Fir Needles)
CarbohydrateHPLC56
Sugars
(Milk)
CarbohydrateHPLC59
Sugars
(Tabacco)
CarbohydrateHPLC8
SulfateAnionHPLC106
SurfactantsDetergentHPLC145
SyringaldehydeAroma CompoundHPLCAN1
Tartaric AcidOrganic AcidHPLC38
TaurineAmino AcidHPLCAN1
TergitolDetergentHPLC61
Tetracosanoic AcidFatty AcidSFC3
TetradecanolFatty AlcoholSFC34
ThreonineAmino AcidHPLCAN1114
Alpha – TocopherolVitaminHPLC97
Beta – TocopherolVitaminHPLC97
Delta – TocopherolVitaminHPLC97
Gamma – TocopherolVitaminHPLC97
TriacontanolFatty AlcoholSFC34
TrilaurinLipidSFC4
TrimyristinLipidSFC4
TrioleinLipidHPLC99
TripalmitinLipidHPLCAN1
TripalmitinLipidSFC4
TristearinLipidSFC4
Triton X 100DetergentHPLC22
TryptophanAmino AcidHPLCAN1113
TyrosineAmino AcidHPLCAN1113
UreaCarbamideHPLC78
ValineAmino AcidHPLCAN1113
Vanillic AcidAroma CompoundHPLCAN1
VanillinAroma CompoundHPLCAN1
Vitamin AVitaminHPLC100
Vitamin B3VitaminHPLCAN1
Vitamin B6VitaminHPLCAN1
Vitamin CVitaminHPLCAN1
Vitamin D2VitaminHPLC101
Vitamin EVitaminHPLC100
Vitamin E1VitaminHPLC101
Vitamin KVitaminHPLC100
Vitamin K1VitaminHPLC101
Xylene SulfonateDetergentHPLC145
XylitolPolyolHPLCAN1
XylitolPolyolSFC49
XyloseCarbohydrateHPLC76
Zwittergent 3 14DetergentHPLC61