SEDERE has generated a large number of application notes that describe the very extensive use of the SEDEX Low-Temperature Evaporative Light-Scattering Detection in LC and SFC. Although this is not an exhaustive list, it provides several examples showing how the detector is used to solve a broad range of analytical problems.
For more complete and recent information on ELSD technology and applications, you can also refer to our SEDERE ELSD Bibliography.
Application List table (Sorted alphabetically)
Note: the application note numbered 1 to 141 are old historical application notes. Application notes numbered “ANXXX” are new applications. Clicking on the application note will either provide access to the PDF of the application note or a dedicated webpage.
Technique: CCC=Counter Current Chromatography, GPC=Gel Permeation Chromatography, HPLC=High Performance Liquid Chromatography, SFC=Supercritical Fluid Chromatography.
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Compound | Chemical Class | Technique | Application Number |
Acesulfam – K | Sweetener | HPLC | AN1 – 144 |
Acetylenecarboxilic Acid | Organic Acid | HPLC | 91 |
Aconitic Acid | Organic Acid | HPLC | 102 |
Alanine | Amino Acid | HPLC | 114 – 123 |
Aliphatic Alcohols | Fatty Alcohol | SFC | 34 |
Alkyl Glucosinolates | Thioglucoside | HPLC | 73 |
Alkylglycosides | Detergent | HPLC | 25 |
Alkylglycosides | Detergent | SFC | 27 |
Androsterone | Steroid | HPLC | 28 |
Arabinose | Carbohydrate | HPLC | AN1 |
Arachidonic Acid | Fatty Acid | HPLC | 31 |
Arginine | Amino Acid | HPLC | AN1 – 90 |
Asparagine | Amino Acid | HPLC | 113 |
Aspartame | Sweetener | HPLC | AN1 – 144 |
Aspartic Acid | Amino Acid | HPLC | 114 |
Bisulfan | Sulfonic Ester | HPLC | 82 |
Bromide | Anion | HPLC | 145 |
Caffeine | Alkaloid | HPLC | AN1 |
Caffeine | Alkaloid | SFC | 12 |
Calcium | Cation | HPLC | 106 |
Beta Carotene | Terpenoid | HPLC | 100 |
Cerebroside | Phospholipid | HPLC | 5 |
Cetylbetaine | Detergent | HPLC | 145 |
Cetylpyridinium Chloride | Aromatic | HPLC | 14 |
Cetrimide | Antiseptic | HPLC | 103 |
Chloramphenicol | Antibiotic | SFC | 12 |
Chloride | Anion | HPLC | AN1 – 106 |
Cholesterol | Steroid | HPLC | 41 |
Citric Acid | Organic Acid | HPLC | 38 |
Citrulline | Amino Acid | HPLC | 125 |
Corticosterone | Steroid | HPLC | 92 |
Coumarin | Aroma Compound | HPLC | AN1 |
Cyclamate | Sweetener | HPLC | AN1 – 144 |
Cyclodextrins | Oligosaccharide | HPLC | 79 |
Cysteine | Amino Acid | HPLC | AN1 – 114 – 115 |
Decanoic Acid | Fatty Acid | HPLC | 32 |
Decyl Beta – D Glucopyranoside | Detergent | HPLC | 25 |
Decyl Beta – D Maltoside | Detergent | HPLC | 25 |
Decyl Sulfate | Detergent | HPLC | 145 |
Dehydro – epi – Andosterone | Steroid | HPLC | 28 |
Deoxyribose | Carbohydrate | HPLC | 74 |
Deoxyribose | Carbohydrate | SFC | 49 |
Dextrans | Carbohydrate | HPLC | 11 |
Dextrose (D – Glucose) | Carbohydrate | HPLC | 144 |
Dimyristolphosphatidyl Choline | Phospholipid | HPLC | 95 |
Diolein | Lipid | HPLC | 99 |
Dimyristolphosphatidyl Glycol | Phospholipid | HPLC | 95 |
Dipalmitin-1,2 | Lipid | HPLC | AN1 |
Dipalmitin-1,3 | Lipid | HPLC | AN1 |
Docosanoic Acid | Fatty Acid | SFC | 3 |
Docosanol | Fatty Alcohol | SFC | 34 |
Dodecylcyclophosphoethanolamine | Phospholipid | HPLC | 83 |
Dodecylcyclophophocholine | Phospholipid | HPLC | 83 |
Dodecylsulfate | Detergent | HPLC | 145 |
Dehydrophenylalanine | Amino Acid | HPLC | 126 |
Eicosanol | Fatty Alcohol | SFC | 34 |
Ergocalciferol | Vitamin | HPLC | 101 |
Erythritol | Polyol | HPLC | AN1(2 methods) |
Estradiol | Steroid | HPLC | 29 |
Estrone | Steroid | HPLC | 29 |
Ethiocolanone | Steroid | HPLC | 28 |
Ethylene Glycol | Glycol | HPLC | 141 |
Ethylvanillin | Aroma Compound | HPLC | AN1 |
Fatty Acids | Fatty Acid | CCC | 48 |
Fluorodopa | Amino Acid | HPLC | 133 |
Fructose | Carbohydrate | HPLC | AN1 – 1 – 8 – 11 – 44 – 74 – 75 – 77 – 143 |
Fructose | Carbohydrate | SFC | 10 – 49 – 50 |
Fructose (Beet) | Carbohydrate | HPLC | 45 |
Fructose (Chervil Root) | Carbohydrate | HPLC | 47 |
Fructose (Tabacco) | Carbohydrate | HPLC | 46 |
Fumaric Acid | Organic Acid | HPLC | 38 |
Galactose | Carbohydrate | HPLC | 59 76 |
Ginseng Saponins | Terpenoid | HPLC | 60 |
Glucose | Carbohydrate | HPLC | AN1 – 1 |
Glucose | Carbohydrate | SFC | 10 – 49 – 50 |
Glucose (Beet) | Carbohydrate | HPLC | 45 |
Glucose (Chervil Root) | Carbohydrate | HPLC | 47 |
Glucose (Tabacco) | Carbohydrate | HPLC | 46 |
Glutamic Acid | Amino Acid | HPLC | AN1 – 115 |
Glutamine | Amino Acid | HPLC | 114 |
Glycerol | HPLC | AN1(2 methods) | |
Hexacameg | HPLC | 84 | |
Hexacosanol | Fatty Alcohol | SFC | 34 |
Hexadecanol | Fatty Alcohol | SFC | 34 |
Hexyl Beta – D Glucopyranoside | Detergent | HPLC | 25 |
Histidine | Amino Acid | HPLC | AN1 – 113 |
Hormonal Steroids | Steroid | HPLC | 28 |
Inositol | Polyol | HPLC | AN1 |
Inositol Phophate | Polyol | HPLC | 80 |
Isoleucine | Amino Acid | HPLC | AN1 – 113 |
Lactose | Carbohydrate | HPLC | 11 |
Lactulose | Carbohydrate | HPLC | 105 |
Lauric Acid | Fatty Acid | HPLC | 40 |
Lauric Acid | Fatty Acid | SFC | 3 |
Lauryldimethylbenzyl Ammonium Chloride | Detergent | HPLC | 145 |
Laurylpyridium Chloride | Detergent | HPLC | 145 |
Leucine | Amino Acid | HPLC | AN1 – 90 |
Linoleic Acid | Fatty Acid | HPLC | 81 97 |
Lipid Placebo | Lipid | HPLC | 95 |
Lubrol | Detergent | HPLC | 61 |
Lysine | Amino Acid | HPLC | AN1 – 90 |
Lysophosphatidyl Choline | Phospholipid | HPLC | 5 |
Lysophosphatidyl Ethanolamine | Phospholipid | HPLC | 98 |
Magnesium | Cation | HPLC | AN1 –106 |
Malic Acid | Organic Acid | HPLC | 38 |
Maltodextrins | Polysaccaride | HPLC | 35 |
Maltose | Carbohydrate | HPLC | AN1 |
Mannitol | Polyol | HPLC | 44 |
Mannitol | Polyol | SFC | 50 |
Mannose | Carbohydrate | HPLC | 44 |
Mannose | Carbohydrate | SFC | 49 |
Melibiose | Carbohydrate | HPLC | 77 |
Meso – Erythritol | Polyol | SFC | 49 |
Methyl a,b -D Glucopyranoside | Detergent | HPLC | 25 |
Methionine | Amino Acid | HPLC | AN1 – 113 |
M-Inositol | Polyol | HPLC | 76 |
Monoolein | Lipid | HPLC | 99 |
Monopalmitin | Lipid | HPLC | AN1 |
Morphine | Alkaloid | SFC | 33 |
Myristic Acid | Fatty Acid | SFC | 3 |
Narcotine | Alkaloid | SFC | 33 |
Neohesperidin Dihydrochalcone | Sweetener | HPLC | AN1 |
Neotame | Sweetener | HPLC | AN1 |
Nitrate | Anion | HPLC | 106 |
Norleucine | Amino Acid | HPLC | 131 |
Norvaline | Amino Acid | HPLC | 132 |
Octadecanol | Fatty Alcohol | SFC | 34 |
Octyl Beta – D Galactopyranoside | Detergent | HPLC | 25 |
Octyl Beta – D Galactopyranoside | Detergent | SFC | 27 |
Octyl Beta – D Glucopyranoside | Detergent | HPLC | 25 |
Octyl Beta – D Glucopyranoside | Detergent | SFC | 27 |
Octyl Beta – D Xylopyranoside | Detergent | HPLC | 25 |
Octyl Beta – D Xylopyranoside | Detergent | SFC | 27 |
Octyl Beta – Glucoside | Detergent | HPLC | 61 |
Oleic Acid | Fatty Acid | HPLC | 97 |
Opium Alkaloids | Alkaloid | SFC | 33 |
Oxytocyn Acetate | Peptide | HPLC | 117 |
Palmitic Acid | Fatty Acid | HPLC | AN1 – 97 |
Palmitic Acid | Fatty Acid | SFC | 3 |
Parafilm | Hydrocarbon | HPLC | 42 |
Parafilm | Hydrocarbon | SFC | 43 |
Para-hydroxy-Benzaldheyde | Amroma Compound | HPLC | AN1 |
Peptides | Peptide | HPLC | 93 |
Phenobarbital | Anticonvulsant | SFC | 12 |
Phenylalanine | Amino Acid | HPLC | AN1 – 113 |
Phenylbutazone | NSAID | SFC | 12 |
Phosphatidic Acid | Phospholipid | HPLC | 5 |
Phosphatidyl Choline | Phospholipid | HPLC | 5 |
Phosphatidyl Ethanolamine | Phospholipid | HPLC | 5 |
Phosphatidyl Glycerol | Phospholipid | HPLC | 98 |
Phosphatidyl Inositol | Phospholipid | HPLC | 5 |
Phosphatityl Serine | Phospholipid | HPLC | 5 |
Pinitol | Polyol | HPLC | 56 |
Polybutylene Glycol | Polymer | HPLC | 86 |
Polyethoxylated Alcohols | Polymer | HPLC | 87 |
Polyethoxylated Alcohols | Polymer | SFC | 87 |
Polyethylene Bimodal (High MV) | Polymer | GPC | 70 |
Polyethylene Glycol PEG 10 Tridecyl Ether | Detergent | HPLC | 61 |
Polyethylene Glycol PEG 1450 | Polymertd> | HPLC | 54 |
Polyethylene Glycol PEG 1450 | Polymer | SFC | 88 |
Polyethylene Glycol PEG 300 | Polymer | HPLC | 21 |
Polyethylene Glycol PEG 300, 400 | Polymer | SFC | 51 |
Polyethylene Glycol PEG 400 | Polymer | HPLC | 23 |
Polyethylene Glycol PEG 600 | Polymer | HPLC | 24 |
Polyethylene (NBS 1475) | Polymer | GPC | 69 |
Polyoxyethylene Alcohol C12 E7 | Polymer | HPLC | 19 |
Polyoxyethylene Alcohol C12 E9 | Polymer | HPLC | 17 |
Polyoxyethylene Alcohol C16 E7 | Polymer | HPLC | 20 |
Polyoxyethylene Alcohol C16 E10 | Polymer | HPLC | 18 |
Polyoxyethylene Alcohol C18 E10 | Polymer | HPLC | 16 |
Polyoxyethylene Alcohols | Polymer | HPLC | 89 |
Polysaccharides (In Beer) | Carbohydrate | HPLC | 9 |
Polysorbate 20 | Polymer | HPLC | 15 |
Polystyrene (Dow 1683) | Polymer | GPC | 68 |
Polystyrene Standards | Polymer | GPC | 62 – 63 – 64 – 65 – 66 – 67 |
Potassium | Cation | HPLC | AN1 – 106 – 107 – 111 |
Prednisolone | Steroid | SFC | 12 |
Progesterone | Steroid | HPLC | 28 |
Proline | Amino Acid | HPLC | 113 – 114 – 134 |
Raffinose | Carbohydrate | HPLC | 1 – 11 – 74 – 75 – 77 |
Raffinose | Carbohydrate | SFC | 10 |
Raffinose (Beet) | Carbohydrate | HPLC | 45 |
Rebaudioside A (from Stevia) | Sweetener | HPLC | AN1(2methods) |
Rhamnose | Carbohydrate | HPLC | AN1 – 74 |
Saccharin | Sweetener | HPLC | AN1 – 144 |
Serine | Amino Acid | HPLC | 114 |
Sodium Dodecyl Sulfate | Detergent | HPLC | 61 |
Sodium | Cation | HPLC | AN1 – 106 |
Sorbitol | Polyol | HPLC | AN1(2 methods) – 1 |
Sorbitol | Polyol | SFC | 50 |
Soybean Oil (Hydrolyzed) | Lipid | HPLC | 118 |
Sphingomyelin | Phospholipid | HPLC | 5 |
Stachyose | Carbohydrate | HPLC | 75 |
Stearic Acid | Triglycerides | HPLC | 97 |
Stearic Acid | Triglycerides | SFC | 3 |
Stigmasterol | Steroid | HPLC | 97 |
Succinic Acid | Organic Acidtd> | HPLC | 38 |
Sucralose | Sweetener | HPLC | AN1 – 143 |
Sucrose (Saccharose) | Carbohydrate | HPLC | AN1 – 1 – 8 – 11 – 74 – 75 – 77 – 143 |
Sucrose (Saccharose) | Carbohydrate | SFC | 10 |
Sucrose (Beet) | Carbohydrate | HPLC | 45 |
Sucrose (Chevil Root) | Carbohydrate | HPLC | 47 |
Sucrose (Tabacco) | Carbohydrate | HPLC | 46 |
Sugars (Mono-Oligosaccharides) | Carbohydrate | HPLC | 76 |
Sugars (Douglas Fir Needles) | Carbohydrate | HPLC | 56 |
Sugars (Milk) | Carbohydrate | HPLC | 59 |
Sugars (Tabacco) | Carbohydrate | HPLC | 8 |
Sulfate | Anion | HPLC | 106 |
Surfactants | Detergent | HPLC | 145 |
Syringaldehyde | Aroma Compound | HPLC | AN1 |
Tartaric Acid | Organic Acid | HPLC | 38 |
Taurine | Amino Acid | HPLC | AN1 |
Tergitol | Detergent | HPLC | 61 |
Tetracosanoic Acid | Fatty Acid | SFC | 3 |
Tetradecanol | Fatty Alcohol | SFC | 34 |
Threonine | Amino Acid | HPLC | AN1 – 114 |
Alpha – Tocopherol | Vitamin | HPLC | 97 |
Beta – Tocopherol | Vitamin | HPLC | 97 |
Delta – Tocopherol | Vitamin | HPLC | 97 |
Gamma – Tocopherol | Vitamin | HPLC | 97 |
Triacontanol | Fatty Alcohol | SFC | 34 |
Trilaurin | Lipid | SFC | 4 |
Trimyristin | Lipid | SFC | 4 |
Triolein | Lipid | HPLC | 99 |
Tripalmitin | Lipid | HPLC | AN1 |
Tripalmitin | Lipid | SFC | 4 |
Tristearin | Lipid | SFC | 4 |
Triton X 100 | Detergent | HPLC | 22 |
Tryptophan | Amino Acid | HPLC | AN1 – 113 |
Tyrosine | Amino Acid | HPLC | AN1 – 113 |
Urea | Carbamide | HPLC | 78 |
Valine | Amino Acid | HPLC | AN1 – 113 |
Vanillic Acid | Aroma Compound | HPLC | AN1 |
Vanillin | Aroma Compound | HPLC | AN1 – |
Vitamin A | Vitamin | HPLC | 100 |
Vitamin B3 | Vitamin | HPLC | AN1 |
Vitamin B6 | Vitamin | HPLC | AN1 |
Vitamin C | Vitamin | HPLC | AN1 |
Vitamin D2 | Vitamin | HPLC | 101 |
Vitamin E | Vitamin | HPLC | 100 |
Vitamin E1 | Vitamin | HPLC | 101 |
Vitamin K | Vitamin | HPLC | 100 |
Vitamin K1 | Vitamin | HPLC | 101 |
Xylene Sulfonate | Detergent | HPLC | 145 |
Xylitol | Polyol | HPLC | AN1 |
Xylitol | Polyol | SFC | 49 |
Xylose | Carbohydrate | HPLC | 76 |
Zwittergent 3 14 | Detergent | HPLC | 61 |